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For Laboratory Research Use Only
Not intended for human or veterinary use.
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5-Amino-1MQ is a small-molecule nicotinamide N-methyltransferase (NNMT)
inhibitor supplied for laboratory research use only.
Published scientific literature has investigated 5-Amino-1MQ and NNMT inhibition in
relation to nicotinamide metabolism, methyltransferase biology and cellular
metabolism research models.
Product Name: 5-Amino-1MQ
Product Type: Small-Molecule NNMT Inhibitor
Amount: 50 mg / 1000 mg
Form: Powder
Purity: ≥99%
Storage: 2–8°C
Batch Testing: Batch-Specific COA Available
Intended Use: Research Use Only
Each batch is linked to a batch-specific Certificate of Analysis (COA).
Available documentation may include purity testing, identity verification, and batch-
related analytical data.
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, et al.
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Nature. 2014;508(7495):258–262.
PMID: 24717514 
DOI: 10.1038/nature13198
Neelakantan H, Vance V, Wetzel MD, Wang HYL, McHardy SF, Finnerty CC, et al.
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-
methyltransferase reverse high fat diet-induced obesity in mice. Biochemical Pharmacology. 2018;147:141–152.
PMID: 29155147
DOI: 10.1016/j.bcp.2017.11.007
Awosemo O, Neelakantan H, Watowich S, Ma J, Wu L, Chow DS, et al.
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in
rat plasma: Application to pharmacokinetic and oral bioavailability studies.
Journal of Pharmaceutical and Biomedical Analysis. 2021;204:114255.
PMID: 34304009
DOI: 10.1016/j.jpba.2021.114255
Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H.
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic
dysfunction.
Diabetes, Obesity and Metabolism. 2024;26(11):5272–5282.
PMID: 39161060
DOI: 10.1111/dom.15879
Product Name: 5-Amino-1MQ
Product Type: Small-Molecule NNMT Inhibitor
Amount: 50 mg / 1000 mg
Form: Powder
Purity: ≥99%
Storage: 2–8°C
Batch Testing: Batch-Specific COA Available
Intended Use: Research Use Only
This product is supplied strictly for laboratory research purposes.
It is not intended for human use, veterinary use, diagnostic applications, or
therapeutic and clinical applications.
True Peptides does not provide dosing guidance, administration instructions, or
usage recommendations.
Product Name: 10-Amino-1MQ 50 mg
LOT Number: 240710A
Expiration Date: July 18, 2028
Storage Conditions: 2–8 °C, unless otherwise specified
Use Category: Research Use Only
This batch is linked to analytical documentation intended to support traceability and laboratory recordkeeping.
The COA may include:
• batch identification
• analytical purity results
• identity verification
• method reference information
This page applies only to the lot number listed above.
Documentation shown here is batch-specific and should not be used as a reference for other lots or product versions.
This material is supplied strictly for laboratory research purposes.
It is not intended for:
• human use
• veterinary use
• diagnostic applications
• therapeutic or clinical applications
True Peptides does not provide dosing guidance, administration instructions, or usage recommendations.
All analytical data provided is batch-specific and linked to the corresponding product.
Transparency in documentation allows for:
True Peptides prioritizes accessible and verifiable documentation as a core part of its quality framework.
Peptide materials are supplied as lyophilized powders.
Recommended storage: 2–8°C refrigerated, unless otherwise specified.
Proper storage conditions are required to maintain material integrity. Stability may vary depending on peptide structure and environmental exposure.
Handling should be performed within controlled laboratory conditions.
